+ 86 (1812) 4514114 [mailaka voaaro]

Raw Tadalafil vovoka (171596-29-5)

(1 mpanjifa famerenana)

Ny tsiranoka vita amin'ny raboka Tadalafil amin'ny anaran'ny Cialis dia ampiasaina mba hanasitranana dysfunction erectile (impotence) sy ny soritr'aretin'ny prostatic malemy .........

Status: Amin'ny famokarana maodely
Unit: 25kg / Drum
fahafahana: 1190kg / volana


Tadalafil powder video

Base Information

Product Name Tadalafil poids
Anarana simika (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
Brand Name Cialis, Adcirca
Drug Class PAH, PDE-5 Inhibitors; Phosphodiesterase-5 Inhibitors Enzyme
CAS Number 171596-29-5
molekiolan'ny Formula C22H19N3O4
molekiolan'ny Wvalo 389.4
Monoisotopic Mass 389.138 g / mol
mitsonika Point 298-300 ° C
Freezing Point 2 ℃
Ny antsasaky ny biolojia 17.5 ora
Color Mavokely ho an'i Cyrstalline Solid
Solubility (78 mg / ml amin'ny 25 ° C), dichloromethane et ethanol (<1 mg / ml à 25 ° C)
Storage Temperature Tehirizina amin'ny hafanana eo anelanelan'ny 59 ° F sy 86 ° F (15 ° C sy 30 ° C). Aza mitahiry izany fanafody izany any amin'ny faritra marefo na maivana.
Tadalafil Application Taratasy fanenan-koditra vita amin'ny tavy Tadalafil, siramamy ara-piraisana, kafe ara-pananahana ets.


Tadalafil, (6R-trans)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1', 2' :1,6]pyrido[3,4-b]indole-1,4-dione (Cialis), is a kind of PDE5 inhibitor and an orally administered drug. It is a b-carboline derivative and it is structurally distinct from vardenafil (Levitraw) and sildenafil (Viagraw), both of which are PDE5 inhibitors based on a fused pyrimidine core structure. Tadalafil powder (CAS 171596-29-5) increase the blood flow into the corpus cavernosum by relaxing the blood vessels muscles, and this enables a man to achieve an erection. Tadalafil powder was approved by the United States (U.S.) Food and Drug Administration (FDA) in 2003 for the treatment of erectile dysfunction (ED), and marketed worldwide under the brand name Cialis. It is also used to treat pulmonary arterial hypertension and benign prostatic hyperplasia, a condition in which the prostate gland becomes enlarged, causing problems with urination.

Tadalafil’s distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the “weekend pill.” This longer half-life also is the basis of current investigation for tadalafil’s use in pulmonary arterial hypertension as a once-daily therapy.

Fomba fiasa

Penile erection during sexual stimulation is achieved by the relaxation of penile arteries and corpus cavernosal smooth muscles, leading to increased blood flow to the organ. This relaxation allows for increased blood flow through the penile arteries, while this blood fills two chambers inside the penis called the corpora cavernosa. As the chambers fill with blood, the penis grows rigid. Erection ends when the muscles contract and the accumulated blood can flow out through the penile veins.

This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells and then controls the dilation and contraction of the blood vessels that carry blood to and from the penis. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum, and is degraded by the cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum located around the penis. Tadalafil inhibits PDE5 and thereby enhances by increasing the amount of cGMP available. Tadalafil stops PDE5 from destroying cGMP and then increases the available cGMP to achieve erectile function and causes the erection to last for longer.

However, as the half-life of Tadalafil is relatively short, its effect wears off in the course of 2 days making PDE5 come back and your sex health – get worse. You may need to take longer to achieve the effect you want, such as low-strength Cialis 4-5 days for 4-5 days.


  • Erectile dysfunction (ED)
  • Pulmonary arterial hypertension
  • Benign prostatic hyperplasia
  • Analgesic
  • Norepinephrine uptake blocker
  • Mu-opiod receptor agonist

Recommended Tadalafil powder Dosage

Cialis comes in yellow, film-coated and almond-shaped tablets in 5, 10 and 20 milligram (mg) doses. The recommended starting dose of Cialis powder for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity.

A first dose is 10 milligrams (mg) at least 30 minutes before sexual activity. The dose can increase to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. But, the maximum is 20 mg as a single dose. The maximum recommended dosing frequency is once per day in most patients. it should not should take no more than one dose in 24 hours. Patients who expect to be sexually active at least twice a week can take a daily dose of 5 mg, and this may be reduced to 2.5 mg once daily, depending on the individual reaction.

Ny vovobam-panafody sikia ampiasaina raha ilaina dia naseho hanatsara ny erectile raha oharina amin'ny plasbo hatramin'ny ora 36 taorian'ny dosing. Noho izany, rehefa manoro hevitra ny marary amin'ny fampiasana tsara ny voly Cialis, dia tokony hodinihina izany.

It is worth noting that an erection will not occur just by taking a pill. And do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension. Beside, Tadalafil for erectile dysfunction is only for use by adults aged 18 years and above.


♦ Tadalafil powder may help relax the muscle in your prostate and bladder. This could help improve your BPH symptoms.

♦ To improve ED symptoms, tadalafil powder helps increase blood flow to the penis. This can help you get and keep an erection. For tadalafil powder to help you have an erection, you need to be sexually aroused.

♦ For PAH, tadalafil powder works to improve your ability to exercise by relaxing blood vessels in your lungs. This increases blood flow.

Side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Please check the following side effects of tadalafil powder:

Ny vokatra iombonana iombonana

▪ aretina

▪ kivy be

▪ fanaintainana

▪ Aretina

▪ milomano (hoditra mena)

▪ siramamy na mandroso

▪ aretim-pivalanana

Rare but serious side effects

A prolonged erection that can lead to damage to the penis, vision problems, and hearing loss.

Raha mora ny vokatr'izany, dia mety hiala ao anatin'ny andro vitsivitsy na herinandro vitsivitsy izy ireo. Raha toa ka matanjaka kokoa izy ireo na tsy mandeha, dia miresaha amin'ny dokotera na pharmacista anao.

People with the following conditions should not take Cialis powder unless a physician agrees:

Heart rhythm problems, angina, or any kind of heart disease

High or low blood pressure

Congestive heart failure or stroke within the last 6 months, or myocardial infarction within the last 3 months

Sickle cell anemia, multiple myeloma, hemophilia, leukemia, or another blood disorder

Ny fihenan'ny pneoma na ny voa

Stomach ulcer

Retinitis pigmentosa

Structural deformity of the penis, such as Peyronie’s disease

Any health condition for which they have been advised not to have sexual intercourse

Tadalafil interaction

When you use tadalafil, there may other drug which can affect the drug, which may lead to side effects. Drug interactions may change how your medications work or increase your risk for serious side effects.

Tadalafil has a modest synergistic effect on the nitrate-induced reduction in blood pressure. Tadalafil can cause a serious drop in your blood pressure when used with nitrates, which can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use tadalafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called “poppers” containing amyl or butyl nitrite.

Raha toa ka mandray fanafody alpha-blocker (toy ny doxazosin, tamsulosin) ianao amin'ny fanafarana prostate / bPH na avo lenta ambony, ny tosidranao dia mety ho lasa ambany loatra ka mety hitarika ho amin'ny fahatarany na ny alahelo. Ny dokotera dia mety hanomboka fitsaboana miaraka amin'ny tadalafil kely ambany na manitsy ny fanafody alpha blocker mba hampihenana ny mety hiterahanao ny tsindry ambany.

In clinical studies, significant rates of response were reported up to 36 h following drug ingestion. Tadalafil is predominantly metabolized in the liver by CYP3A4 to entities that are not active against PDE5 and excreted mainly as metabolites in the feces and the urine. The pharmacokinetics of tadalafil are unaffected by factors such as intake of food and alcohol, age, the presence of diabetes, and mild or moderate hepatic insufficiency. The most common drug-related adverse events are headache, back pain, dyspepsia, and myalgia. At 10 and 20 mg doses, Tadalafil does not have a significant effect on blood pressure and heart rate and does not result in increased instances of myocardial infarction. Rare reports of prolonged erections greater than 4 h and priapism have been noted with the use of tadalafil. Priapism, if not treated properly, can result in irreversible damage to the erectile tissue. Patients who have an erection lasting greater than 4 h are advised to seek emergency medical attention. In diabetic patients, improvement of erectile function by tadalafil is irrespective of the type of diabetes and the type of diabetic therapy.

Ny fanafody hafa dia mety hisy fiantraikany amin'ny fanesorana ny tadalafil amin'ny vatanao, izay mety hisy fiantraikany amin'ny fomba iadian'ny tadalafil. Anisan'izany ny antibiotika azole (toy ny itraconazole, ketoconazole), antibiôtika macrolide (toy ny clarithromycin, erythromycin), ny hemôglomycin proteases HIV (toy ny fosamprenavir, ritonavir), ny hepatitis C virus-inhibitors (toy boceprevir, telaprevir), rifampin, .

Levitra no prescription, levitra vardenafil hcl, levitra vardenafil generic, vardenafil and vardenafil.

Regarding tadalafil interaction with other drugs still have so much, if you want to use a drug with tadalafil powder (CAS 171596-29-5), first remember to consult your doctor and he will give you a professional and reliable advice. Fitsaboana goavambe ho an'ny Tadalafil Generic For ED

Fampahalalana fanampiny

Tadalafil powder, sildenafil powder, and vardenafil powder all act by inhibiting the PDE5 enzyme, but these drugs also inhibit PDE enzymes 6, 1, and 11 in varying degrees. For example, Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil. Some sildenafil users see a bluish tinge and have a heightened sensitivity to light because of PDE6 inhibition. Besides, Sildenafil and vardenafil also inhibit PDE1 more than tadalafil. PDE1 is found in the brain, heart, and vascular smooth muscle. It is thought that the inhibition of PDE1 by sildenafil and vardenafil leads to vasodilation, flushing, and tachycardia.

Compared to the performance in PDE6 and PDE1, tadalafil performed more prominently on PDE11. PDE11 is expressed in skeletal muscle, the prostate, the liver, the kidney, the pituitary gland, and the testes. However, the effects on the body of inhibiting PDE11 are not known.


References & citations

Fitsaboana goavambe ho an'ny Tadalafil Generic For ED


  • 1.National Foibe momba ny fampahalalana momba ny biôsechnologie, Etazonia. Tranombokim-pirenena momba ny fitsaboana, Tadalafil, fizarana Pubchem 1-10.
  • Levitra and cialis (Tadalafil), Viagra (Sildenafil), and Other Drugs Cheap and Safely Online, Published, 2 Dec 13, page, Cialis (Tadalafil): Use, Dosage, Side Effects Information 2017-5
  • 3.James Lee Anderson, Cialis, Tadalafil: Ny fitsaboana Erectile Dysfunction, Symptoms of Hyperplasia Prostatic Prostatic, and Pulmonary Hypertension Pulmonary, CreateSpace Independent Publishing Platform, 26 Mar 2015, page 5-47.

1 famerenana for Raw Tadalafil vovoka (171596-29-5)

  1. phcoker -

    Tovolahy Tadalafil nahazo tsindrona mba hitsapana, ny vokatra azo avy amin'ny test dia tena avo lenta sy fahamendrehana!

Add ny famerenana

Ny adiresy email dia tsy ho namoaka. Mitaky saha dia marika *